Before Europeans arrived, the Mohican had settlements along the Hudson near where it meets the Mohawk River. The land around the Poesten Kill, called Panhooseck, belonged to Skiwias, the land around the Wynants Kill, Paanpack, to Peyhaunet, and the land between the creeks, now downtown and South Troy, to Annape. These parcels were sold to the Dutch between 1630 and 1657, each purchase overseen by Skiwias as sachem, and more than 75 Mohicans took part in deed signings in the 17th century.
More about Troy
The site was part of Rensselaerswyck, the patroonship of Kiliaen van Rensselaer. Dirck Van der Heyden, one of the first settlers, bought a 65-acre farm in 1707, which was laid out as a village in 1787. The community, known as Ashley's Ferry, adopted the name Troy, after the city of Homer's Iliad, in 1789, part of a fashion for classical names in post-Revolutionary New York seen also in Syracuse, Rome, Utica and Ithaca. The Town of Troy was formed in 1791 from part of the manor, Troy became a village in 1801 and was chartered as a city in 1816.
In the War of 1812, troops were led by Stephen Van Rensselaer of Troy, and army supplies were shipped through the town. According to local lore, the butcher and meatpacker Samuel Wilson, who supplied the army, stamped his barrels "U.S.," which soldiers took to mean "Uncle Sam," meaning Wilson, and Troy claims to be the home of Uncle Sam.
Sources
Wikipedia: Troy, New York