Venice, in Sarasota County, has evidence of Paleo-Indians dating to 8200 B.C., followed by Archaic peoples whose camps and stone tools have been found in the city. When the Spanish arrived in the 1500s, the area lay on the boundary between the Tocobaga and the Calusa, both mound-building peoples.
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The first significant wave of white settlers came in the 1870s, when the place was known as Horse and Chaise, for a carriage-shaped tree formation that guided fishermen. Robert Rickford Roberts homesteaded by what is now Roberts Bay, and in 1883 Francis H. "Frank" Higel came from France with his wife and six sons, bought part of the Roberts homestead for $2,500 and started a citrus business making jams, pickled orange peel, lemon juice and orange wine. Higel opened a post office named Eyry in 1885, which closed that November, and in 1888 another opened under the name he suggested, Venice, for its likeness to the Italian canal city.
During the land boom of the 1920s Dr. Fred H. Albee, an orthopedic surgeon known for bone-grafting operations, bought land from Bertha Palmer to develop Venice and hired planner John Nolen to design the city. Albee sold the land to the Brotherhood of Locomotive Engineers, which kept Nolen as planner.
Sources
Wikipedia: Venice, Florida